Overview
UT Southwestern invites you to join a world-renowned medical and research center committed to excellence, innovation, teamwork, and compassion. Ranked as the number 1 hospital in Dallas–Fort Worth according to U.S. News & World Report, we offer opportunities for career growth, competitive benefits, and a culture of teamwork and professionalism.
Job Summary
Plans, coordinates, directs, and participates in the work of a smaller research project or a major unit of a large research project in the field of specialization for which the incumbent is highly qualified through extensive training and/or experience.
Position
The Levi laboratory in the Division of Burn, Trauma, Acute and Critical Care Surgery in the Department of Surgery has an opening for a Research Scientist with an Osteosarcoma focus to join the team, with a commitment of at least two years. The Research Scientist will support ongoing bench and animal work related to tendon injury/fibrosis, muscle injury/fibrosis, or bone/tendon/muscle regeneration. Duties include routine molecular bench work, animal models (handling, injections, surgeries, sample collection) and downstream processing (histology, immunofluorescent staining and confocal imaging, flow cytometry, cell culture, single-cell and bulk RNA sequencing) under the supervision of the principal investigator.
Laboratory Expectations
- Routine molecular bench work with animal models
- Animal handling, injections, diet maintenance, surgeries, and sample collection
- Downstream processing including histology, immunofluorescent staining and confocal imaging, flow cytometry, cell cultures, and single-cell and bulk RNA sequencing
Preferred Experience
- Molecular biology techniques (PCR, qPCR, Western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9, next-generation sequencing)
- Experience with animal handling, breeding, genotyping, and surgery
- Experience with single-cell transcriptomics
- Experience with histology pipelines from tissue harvest to embedding, sectioning, staining, and confocal microscopy
- Experience with flow cytometry and mass spectrometry
- Excellent written and oral communication and organizational skills
- Ability to analyze data using bioinformatics tools, statistical methods, and relevant software packages
Laboratory Duties
- Animal breeding, genotyping, handling, and surgery
- Molecular biology techniques (PCR, qPCR, Western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9, next-generation sequencing)
- Flow cytometry and mass spectrometry
- Histology pipeline from tissue harvest to embedding, sectioning, staining, and confocal microscopy
- Design and execution of experiments to investigate molecular mechanisms
- Develop and implement standard operating procedures for experimental protocols
- Review and analyze research data
- Adapt techniques as needed based on data
- May collaborate with industrial, governmental, or other groups on progress or results
- Maintain a respectful, inclusive laboratory environment and a clean, functional workspace
- Analyze data using relevant software and statistics; stay current with advances in molecular biology
- Prepare findings for publication and present at meetings
- Contribute to grant writing and fundraising; collaborate with interdisciplinary teams
- Assist in training and supervision of junior personnel
Benefits
UT Southwestern offers a competitive and comprehensive benefits package, including:
- PPO medical plan available day one for full-time employee-only coverage
- 100% coverage for preventive healthcare with no copay
- Paid time off available day one
- Retirement programs through the Teacher Retirement System of Texas (TRS)
- Public Service Loan Forgiveness (PSLF) qualified employer
- Learn more about these and other UT Southwestern employee benefits
Experience and Education
- Education: PhD with major coursework in the field of assignment, or Master’s with major coursework, or Bachelor’s with major coursework
- Experience: 5 years of research experience in the field with PhD and 2 years at Senior Research Associate level (or equivalent), or 7 years with Master’s and 3 years at Senior Research Associate level (or equivalent), or 9 years with Bachelor’s and 4 years at Senior Research Associate level (or equivalent)
Job Duties
- Plan, organize, coordinate, direct, and participate in assigned scientific or medical research projects; select key personnel; determine goals; assign and review work; plan experimental protocols
- Review and analyze data; revise techniques as needed based on data
- Prepare and submit results; assist in preparing papers, reports, and abstracts for publication
- Design, develop, or adapt equipment used in experiments
- Plan and supervise training of technicians and other personnel
- Supervise a team of lower-grade employees
- May confer with external groups on progress or results