Risk Management Manager

Amgen
Los Angeles, US
On-site

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Risk Management Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will leads key capabilities across Risk Analytics & Insights, Risk Systems & Tools, the ISP Safety Program, Risk Management and Special Projects. This role also provides leadership across multi-site strategic initiatives, Crisis Management, and Business Continuity.

This position drives a standardized, risk-based operating framework across Global Facilities Operations (GFO), enabling proactive identification and mitigation of operational and safety risks across a complex network of sites, functions, and Integrated Service Providers (ISPs). Through centralized oversight and advanced analytics—including AI-enabled capabilities—the role enhances enterprise visibility and decision-making.

The Manager also supports the retirement of legacy solutions and the migration of existing and new digital tools to enterprise IS platforms and programs, ensuring scalability, standardization, and long-term sustainability.

As GFO continues to grow in complexity, this role ensures alignment across sites by integrating risk analytics, strengthening ISP safety programs, and advancing crisis management and business continuity capabilities.

This position represents a strategic investment in enhancing safety, improving operational resilience, and enabling data-driven decision-making across GFO and EOS.

The role reports to the Director of Risk Management within Global Facilities Engineering.

  • GFO / ISP Safety Program Management
  • Lead the design, implementation, and continuous improvement of ISP safety programs across GFO sites
  • Establish standardized safety governance, expectations, and accountability frameworks with ISPs
  • Monitor safety performance through scorecards, dashboards, and governance forums
  • Drive Serious Injury & Fatality (SIF) risk reduction strategies focused on high-risk activities
  • Ensure consistent incident reporting, escalation, and investigation processes across the network
  • 2. Risk Analytics & Insights
  • Develop and operationalize risk-based performance indicators to monitor safety and operational risk across GFO
  • Analyze cross-functional datasets to identify emerging risks, systemic issues, and leading indicators
  • Translate complex data into actionable insights to support executive decision-making and prioritization
  • Continual enhancement of predictive risk models to improve early detection and prevention capabilities
  • 3. Risk Systems & Tools
  • Support the retirement of legacy solutions and the migration of both existing and new digital tools to new enterprise IS platforms and programs.
  • Lead evaluation and optimization of risk management platforms, dashboards, and reporting tools
  • Ensure data integrity, consistency, and alignment across enterprise risk systems
  • Identify capability gaps and drive implementation of scalable solutions to enhance risk visibility
  • Streamline workflows through automation and system integration to reduce manual effort
  • 4. Risk Intelligence & Reporting
  • Develop integrated risk intelligence capabilities combining safety, financial, and operational data
  • Identify trends, correlations, and systemic risks to inform strategic decision-making
  • Deliver executive-level reporting on key risks, performance gaps, and mitigation opportunities
  • Enable proactive monitoring through advanced dashboards and data visualization
  • 5. Strategic Initiatives & Special Projects
  • Lead cross-functional, multi-site initiatives focused on risk reduction, safety improvement, and operational efficiency
  • Develop business cases, define success metrics, and ensure delivery of measurable outcomes
  • Drive process standardization, automation, and continuous improvement initiatives
  • Provide leadership in stakeholder alignment, change management, and program execution
  • 6.

Skills & Requirements

Technical Skills

Risk managementSafetyOperations

Employment Type

FULL TIME

Level

Mid-Level

Posted

4/24/2026

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