Scientist II/Sr Scientist I , Analytical R&D

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products.  Our scope includes AbbVie's diverse pipeline of innovative small molecule medicines and spans from the selection of Discovery candidate molecules to Late Stage Clinical.  We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines.  Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.  We are looking for diverse candidates with strong scientific experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Position Description:

For the Scientist II position, we are seeking a highly motivated candidate who can independently develop and optimize new methods and techniques to generate reliable and reproducible data in a timely manner, demonstrate broad and versatile technical expertise. Continuously seek to improve existing laboratory methods and processes. They should demonstrate mastery of broad range of experimental techniques and support early phase development of New Chemical Entities (NCEs) drug substance and drug product in both preclinical and clinical programs. Collaborate within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety (PCS), Process Chemistry, Process Engineering, Drug Product Development (DPD), and Quality Assurance (QA) and CMC-Regulatory.

Responsibilities:

• Performs method development, testing procedures, and implementation of analytical control strategies to help the advancement of drug discovery candidates with some guidance.
• Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical products to further the understanding of emerging cGMP manufacturing processes.
• Responsible for contributing to the analytical aspects of a project while working with other functional areas to advance projects through the development pipeline.
• Utilize understanding of a range of analytical techniques to conduct research and development studies related to small-molecule drug products, active pharmaceutical ingredients, intermediates, starting materials, impurities, and impurity profiling.
• Support new product development with method development and validation, technical transfer packages, and generation of technical data in support regulatory requirements with some guidance.
• Autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
• Formulate conclusions and design follow-on experiments based on multidisciplinary data.
• Process, interpret, and visualize data to facilitate project team decisions.
• Communicate and collaborate with cross-functional groups and departments.
• Demonstrate scientific rigor, initiative and creativity in research or development activities and maintain a high level of productivity in the lab.
• Raises the bar and is never satisfied with the status quo.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, and GxP compliance, where applicable.

Qualifications

• Bachelor’s Degree in Chemistry, Analytical Chemistry, or equivalent education, with typically 7 or more years’ experience or Master’s Degree or equivalent education, with typically 5 or more years’ experience.
• Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of developing and troubleshooting analytical methods with minimal guidance.
• Well versed with hands-on experience with chromatography (HPLC, UPLC, GC) and spectroscopic techniques.
• Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
• Software Proficiency - Expert knowledge of Waters Empower CDS and experience with SLIMS (or similar LIMS systems) for electronic data management.
• Experience in the use of computerized data handling systems.