Senior Biostatistician – Senior Data Scientist/Analyst, OMOP

Syneos Health
Washington, US
Remote

Job Description

Job Description:

  • Collaborate with researchers to understand project requirements and translate them into OHDSI/DARWIN‑compatible solutions
  • Build, validate, and execute OMOP CDM cohorts and analyses using: ATLAS (cohort definition, characterization, exploration) ATHENA (vocabulary browsing, concept sets) ACHILLES (data characterization and quality insights) R packages in the OHDSI/DARWIN ecosystem (for cohort execution, characterization, estimation, and related workflows)
  • Perform analyses using ATLAS and/or Prometheus or via programmatic workflows in R (and Python where appropriate), depending on study needs and platform patterns
  • Customize and extend OHDSI tools and applications as needed to support project- or portfolio-specific requirements
  • Apply and document observational study designs and epidemiologic concepts for RWE (e.g., descriptive epidemiology, cohort designs, self-controlled designs, comparative approaches as applicable)
  • Implement and interpret appropriate statistical methods, including confounding control strategies, time-to-event approaches, sensitivity analyses, and fit-for-purpose evaluations
  • Maintain familiarity with machine learning and statistical concepts to support exploratory modeling, feature engineering, prediction workflows (when relevant), and method selection
  • Develop reusable and maintainable analytic code, prioritizing reproducibility and auditability (clear methods, parameterization, and structured outputs)
  • Incorporate AI-assisted workflows to improve efficiency in: Code generation/refactoring Validation and QA checks Documentation and study write-ups Exploratory analysis and summary generation while ensuring results remain transparent, traceable, and scientifically defensible
  • Use GitHub extensively (branching, pull requests, code reviews, issue tracking) to deliver collaborative, production-grade analytics

Requirements:

  • Masters degree in Statistics or related field
  • Demonstrated experience with OMOP CDM and OHDSI tooling, including ATLAS (or Prometheus), ATHENA, and ACHILLES
  • Proficiency in common OHDSI community languages: SQL and R
  • Strong understanding of observational study design and epidemiologic concepts, with emphasis on RWE
  • Experience working with healthcare data such as EHR and insurance claims, including healthcare data standards and fit-for-purpose evaluation
  • Solid understanding of clinical terminologies such as SNOMED, ICD-9/10, CPT, HCPCS, READ (and related standard vocabularies used in OMOP)
  • Experience with data quality assessment and data validation techniques
  • Proven ability to work in a fast-paced environment, delivering high-quality outputs with strong documentation and collaboration
  • Strong problem-solving ability and comfort working in cross-functional teams
  • Excellent communication skills, with the ability to convey technical concepts to technical and non-technical stakeholders
  • Strong experience developing and maintaining documentation for RWE studies and insight generation
  • Demonstrated willingness and ability to incorporate AI tools into workflows for efficiency and quality

Benefits:

  • company car or car allowance
  • Health benefits to include Medical, Dental and Vision
  • Company match 401k
  • eligibility to participate in Employee Stock Purchase Plan
  • Eligibility to earn commissions/bonus based on company and individual performance
  • flexible paid time off (PTO)
  • sick time

Skills & Requirements

Technical Skills

Omop cdmOhdsi toolingAtlasAthenaAchillesR packagesSqlRPythonObservational study designEpidemiologic conceptsHealthcare dataClinical terminologiesData quality assessmentData validation techniquesMachine learningStatistical methodsConfounding control strategiesTime-to-event approachesSensitivity analysesExploratory modelingFeature engineeringPrediction workflowsAi-assisted workflowsGithubProblem-solvingCommunicationCollaborationBiostatisticsOmop cdmOhdsiHealthcare dataClinical terminologiesData quality assessmentData validation techniquesMachine learningStatistical methodsAi-assisted workflows

Employment Type

FULL TIME

Level

senior

Posted

5/6/2026

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