Senior Portfolio & Delivery Manager

Revolution Medicines
Redwood City, US
On-site

Job Description

About the position

The Senior Manager Portfolio & Delivery advances PMO maturity while ensuring disciplined execution of business system implementations and sustainment initiatives across the organization. This role is responsible for strengthening portfolio governance, modernizing visibility through advanced dashboarding and AI-enabled risk and capacity forecasting, and establishing structured intake and prioritization processes that enable predictable, scalable delivery. In addition, this position directly manages high-impact or strategically significant projects to ensure successful execution and model delivery excellence within the PMO framework. As the organization evolves beyond initial commercial launch, this position ensures IS operates with data-driven transparency, governance rigor, and execution discipline. Key responsibilities include:

Portfolio Strategy & Governance

Advance and formalize the PMO framework to support commercial launch and post-launch scale.

Lead and continuously improve the intake process (business case quality, scoring, prioritization, gating).

Lead development and continuous improvement of portfolio governance standards, controls, and reporting structures.

Operationalize a structured intake process aligned to strategic priorities and resource capacity.

Design and implement a transparent prioritization framework to guide investment decisions.

Strengthen and advance the Technology Review Committee (TRC) through structured scoring, impact analysis, and trade-off visibility.

Shift governance from reactive coordination to proactive decision enablement.

Portfolio Visibility & Predictive Insights

Modernize Project Portfolio Dashboards to provide executive-level visibility into delivery health.

Incorporate AI-enabled risk prediction, capacity modeling, and planning analytics.

Develop forward-looking forecasting models to support budget and resource planning.

Provide leadership with actionable insights on portfolio risk, constraints, and trade-offs.

Project Management & Delivery Leadership

Directly manage complex, high-visibility, or cross-functional business system implementations.

Lead projects from initiation through planning, execution, go-live, and stabilization.

Develop project plans, resource strategies, and risk mitigation approaches.

Monitor scope, budget, timelines, and dependencies in alignment with PMO standards.

Facilitate executive-level status reporting and stakeholder communication.

Intervene proactively to stabilize projects at risk.

Delivery Oversight & Execution Discipline

Oversee active business system implementations and sustainment initiatives across the portfolio.

Ensure consistent application of PMO standards, tools, and reporting across projects.

Monitor cross-functional dependencies, capacity utilization, and execution risks.

Partner with functional IS leaders to align delivery plans with available resources.

Drive continuous improvement in delivery predictability and operational performance.

Serve as a power user for PPM tools (e.g. Smartsheet). Automate reporting where feasible; document processes and run training to uplift adoption.

Strategic Impact

Predictable, scalable delivery through a modern PMO operating model.

Improved portfolio clarity and executive decision-making.

Stronger alignment between strategic priorities and resource allocation.

Reduced delivery volatility and reactive firefighting.

Increased leadership confidence in IS planning and execution.

Responsibilities

  • Advance and formalize the PMO framework to support commercial launch and post-launch scale.
  • Lead and continuously improve the intake process (business case quality, scoring, prioritization, gating).
  • Lead development and continuous improvement of portfolio governance standards, controls, and reporting structures.
  • Operationalize a structured intake process aligned to strategic priorities and resource capacity.
  • Design and implement a transparent prioritization framework to guide investment decisions.
  • Strengthen and advance the Technology Review Committee (TRC) through structured scoring, impact analysis, and trade-off visibility.
  • Shift governance from reactive coordination to proactive decision enablement.
  • Modernize Project Portfolio Dashboards to provide executive-level visibility into delivery health.
  • Incorporate AI-enabled risk prediction, capacity modeling, and planning analytics.
  • Develop forward-looking forecasting models to support budget and resource planning.
  • Provide leadership with actionable insights on portfolio risk, constraints, and trade-offs.
  • Directly manage complex, high-visibility, or cross-functional business system implementations.
  • Lead projects from initiation through planning, execution, go-live, and stabilization.
  • Develop project plans, resource strategies, and risk mitigation approaches.
  • Monitor scope, budget, timelines, and dependencies in alignment with PMO standards.
  • Facilitate executive-level status reporting and stakeholder co

Skills & Requirements

Technical Skills

Smartsheet

Employment Type

FULL TIME

Level

senior

Posted

4/11/2026

Apply Now

You will be redirected to Revolution Medicines's application portal.