Senior Research Associate, Biobank

Job Title: Senior Research Associate, Biobank

Company: SRT Therapeutics

Location: San Diego, CA. 100% on-site.

Reports to: Director of Computational Biology, R&D

Pay Range: $72,000-$118,000

About Us

SRT Therapeutics is a San Diego-based biotech company established in 2024 by the founders

of Prometheus Biosciences, Steph Targan, MD (Cedars Sinai), Janine Bilsborough, Ph.D.

(Cedars Sinai), the scientific team that discovered Tulisokibart (MK7240) and the role of TL1A in

IBD and Scott Glenn and Lauren Otsuki, the drug development team that took Tulisokibart

(MK7240) from academia into the clinic. Building on the demonstrated success of the precision

medicine approach in IBD with Tulisokibart, SRT Therapeutics will expand this approach by

targeting key pathways that not only modulate inflammatory pathways, but also promote tissue

healing in IBD. This strategy will move SRT Therapeutics beyond the current empirical

treatment model to realize the goal of enhancing both outcomes and the quality of care for our

patients.

Position Summary

We are seeking a dynamic and highly motivated Senior Research Associate (SRA) to join our

biobanking team. This is a hands-on role where you will be responsible for the entire lifecycle of

biobank specimens and operations, including receipt, accessioning, assay development,

processing, and analysis. The core of this role is multimodal data generation, including next

generation sequencing (NGS), cell based assays, and imaging. We need an individual who

excels at the "bench-level" challenge of deriving actionable, high-quality multi-modal data from a

broad range of challenging specimen types. You will be the point person for optimizing the

extraction of nucleic acids and proteins from our most difficult and precious samples, including

rare cell types and archival tissues. Your work will serve as the foundation for our precision

medicine approach and will require a mix of technical rigor and a scrappy, solution-oriented

mindset to extract maximal value from every specimen.

Core Responsibilities

• Sample Management: Receive, accession, and process human and model organism

specimens (blood, saliva, fresh, frozen, and archival tissues, among others).

• Sample Processing: Optimize preservation and processing workflows to isolate highquality

nucleic acids and proteins from challenging samples including FFPE, frozen, and

rare cell populations. Purify and bank human blood derived specimens.

• Assay Execution & Development: Develop, run, and scale NGS and other molecular

assays, including qPCR, bulk and single-cell RNA sequencing, DNA sequencing, and

proteomic analysis.

• Quality & Integrity: Maintain the biobank’s integrity through rigorous adherence to

SOPs, meticulous process and QC data capture, and strict chain-of-custody

management.

• Operational Logistics: Manage LIMS data entry, coordinate biobank operations with

internal scientists, external suppliers, and CROs, and assist with off-site backup storage.

• Cross-Functional Collaboration: Partner closely with functional biomarker and

computational biology teams to translate raw samples into high-fidelity data.

Required Qualifications

• Experience: 5+ years of hands-on laboratory experience in biobanking, genomics,

molecular biology, or cell biology, with a focus on NGS assays including single cell and

spatial sequencing. Experience working with challenging sample types including flash

frozen and FFPE archival tissues required. Experience in a start-up environment is

preferred.

• NGS Expertise: Broad and deep experience in NGS library preparation, sequencing,

and assay development. Familiarity with Illumina platforms and high-throughput formats

(96/384-well) is essential.

• Advanced Extractions: Proven track record of successfully extracting high-quality

nucleic acids and cells from difficult samples including archival tissue, low-input

samples, and rare cell types.

• Technical Proficiency: Professional experience with LIMS, sample management

software, and automated liquid handling systems.

• Precision & Rigor: A quality-first mentality with experience developing and working

under SOPs and capturing detailed QC data.

• Communication: Ability to clearly communicate complex processes and findings to both

internal stakeholders and external partners.

Preferred Skills

• Experience running and analyzing multicolor flow cytometry panels.

• Prior experience in a startup or fast-paced biotech environment.

• Knowledge of biomarker discovery and common bioinformatics tools.