Senior Scientist, Biologics Design and Display, Discovery Biologics

Job Description

We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines.

We are seeking a Senior Scientist to join Biologics Design and Display team in the Boston Discovery Biologics group. The successful candidate will be an integral member of the team responsible for conducting in vitro display campaigns to generate novel therapeutic hits and optimized leads. They will directly contribute to the discovery of novel biologics as well as platform build and technology optimization efforts. They will stay current with scientific progress and drive continuous innovation of display technologies to consistently deliver high quality early biologics to support drug discovery across multiple therapeutic areas. As part of project teams, they will collaborate across groups to solve complex problems in disease biology and drug discovery. They will attend scientific conferences, contribute to publications, train and mentor junior stuff and interns, and help to set the group strategy.

We recognize that the diversity in our team is our strength, and we are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviours in working with a diverse group of researchers to drive our core mission.

Responsibilities:

• Perform yeast and phage display based biologics discovery screens to support therapeutic programs

• Execute display-based lead optimization, including display library building, QC, and screening

• Contribute to design and building of novel display libraries

• Routinely use NGS, including NGS library generation, QC, sequencing and data analysis, for hit selection

• Maintain accurate data and experimental records

• Prepare presentations to effectively communicate experimental results in team meetings

• Collaborate across different functional areas within Discovery Biologics and with key stakeholders in other departments

• Stay abreast of external advancements in the relevant scientific fields

• Promote the external reputation of our company’s Discovery Biologics

Qualifications & Experience

• PhD in Biology, Biochemistry, Analytical Chemistry, Bioengineering, Biophysics, Protein Sciences, Pharmaceutics, or a related life sciences discipline with 0-3 years of experience or MS with >5 years of industry experience

• Expertise in using display-based screening methods

• Expertise in molecular biology and high throughput laboratory methodologies

• Strong presentation and publication record

Required skills:

• Deep expertise in both phage and yeast display

• Hands on experience in antibody or other molecular display technologies

• Expertise in NGS technology, including NGS libraries generation, QC, sequencing and sequence analysis

• Strong technical knowledge of molecular biology

• Strong analytical and problem solving skills

• Stay abreast of external advancements in the relevant scientific fields

• Excellent communication and organizational skills

Preferred skills:

• Hands on expertise in display library design and generation

• Knowledge of computational and structure-guided approaches in display library design

• Knowledge of antibody discovery technologies beyond display

• Hands on expertise in using laboratory automation

#EligibleforERP

Required Skills:

Antibodies, Antibody Discovery, Display Technologies, High-Throughput Screening, Molecular Biology Techniques, Next Generation Sequencing (NGS), Phage Display, Yeast Display

Preferred Skills:

Automation

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive enviro