Staff Scientist, Research (Epigenomics)

Natera
Washington, US
Remote

Job Description

Description:

  • Lead and manage the development of innovative NGS-based diagnostic assays from feasibility through optimization.
  • Define project goals and plans with stakeholder input and manage multiple project streams in parallel.
  • Independently design and execute complex laboratory experiments, then analyze and interpret results to guide research direction.
  • Coordinate cross-functional efforts to meet milestones and collaborate with bioinformatics, statistics, and data science teams on experimental design and data analysis.
  • Mentor and guide junior scientists while promoting scientific rigor and best practices.
  • Author protocols, technical reports, study plans, SOPs, and other study documentation.
  • Communicate project progress regularly to stakeholders, departmental meetings, and senior leadership.
  • Contribute to risk management, strategy development, and continuous improvement of scientific workflows.
  • Translate complex biological questions into actionable experiments and scalable solutions.

Requirements:

  • Ph.D. in molecular biology, genomics, or a closely related field.
  • Minimum 8 years of relevant industry experience, or 2+ years of postdoctoral research plus 6+ years in industry.
  • Proven experience designing and advancing NGS-based diagnostics, preferably in oncology.
  • Extensive hands-on experience with NGS platforms, including sample prep, library prep, target enrichment, and sequencing.
  • Experience with target enrichment methods such as multiplex PCR and hybrid capture.
  • Strong understanding of DNA/RNA manipulation and epigenomics/methylation detection.
  • Proficiency in statistical analysis tools such as Excel, JMP, R, or Python.
  • Familiarity with bioinformatics workflows is a plus.
  • Excellent organizational, communication, and time management skills.
  • Up-to-date knowledge of oncology and genomic technology developments.

Benefits:

  • Compensation range of $157,300 to $196,600 USD.
  • Annual performance incentive bonus.
  • Long-term equity awards.
  • Comprehensive health benefits, including medical, dental, and vision coverage.
  • 401(k) with company match.
  • Generous paid time off and company holidays.
  • Pregnancy and baby bonding leave.
  • Fertility care benefits, commuter benefits, and other wellness and work-life benefits.

Skills & Requirements

Technical Skills

Ngs-based diagnosticsOncologyNgs platformsSample prepLibrary prepTarget enrichmentSequencingMultiplex pcrHybrid captureDna/rna manipulationEpigenomicsMethylation detectionStatistical analysisBioinformaticsExcelJmpRPythonCommunicationTime managementGenomicsEpigenomicsOncologyNgs

Salary

$157,300 - $196,600

year

Employment Type

FULL TIME

Level

Mid-Level

Posted

5/2/2026

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