Founding AI Research Scientist - Optexity (USA)

Pear Vc
San Francisco, CA
Remote

Who this role is best for

Founding AI Research Scientists with healthcare domain experience and open-ended problem-solving skills will find this technical and collaborative role in the San Francisco Bay Area.

Best fit for

  • Candidates with a background in clinical reasoning and a desire to publish research in top-tier conferences
    — “multiple published papers in NeurIPS, ICML, CVPR etc
  • Individuals who have trained models from scratch and are comfortable with Python-based workflows
    — “Has trained models before (not just fine-tuned APIs) and is fluent in Python
  • Researchers who thrive in startup environments and prefer speed and ambiguity as defaults
    — “Genuinely wants a startup over big tech — speed and ambiguity as defaults, not exceptions

Things to consider

  • This role demands a high level of ownership and initiative in defining technical agendas
    — “you'll define the agenda as much as execute it
  • The position requires working with proprietary clinical data from hospitals and clinics
    — “Work with real, proprietary clinical data from hospital and clinic partners

How to stand out

  • Highlight your experience in building end-to-end training and evaluation pipelines
    — “Own the training and evaluation pipeline end to end
  • Emphasize your ability to design novel benchmarks for evaluating LLMs
    — “Design and publish benchmarks that expose where current LLMs fall short
  • Demonstrate your experience in solving open-ended problems with minimal structure
    — “Take open-ended problems from question to working model, with minimal predefined structure
Pace · Fast PacedCollaboration · HighAutonomy · HighDecision Impact · CompanyLevel · Mid Level

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • Published research papers
  • Developed clinical reasoning models
Typical background
Master's or higher in ML or related field

Skills & requirements

Required

Machine LearningClinical Reasoning ModelsPythonResearch Experience

Preferred

Llm-powered ProductsHealthcare Datasets

Stack & domain

PythonHealthcare

About the role

Original posting from Pear Vc via Ashby

ABOUT OPTEXITY

Optexity is a product-driven research lab building clinical reasoning and computer use models on data no other lab can reach. We deploy directly inside clinics and hospitals — including systems with no APIs, using integration infrastructure we've built and open-sourced — and in return become their preferred partner. That gives us proprietary clinical reasoning trajectories from practicing physicians, and a feedback loop between real patient encounters, our models, and the products built on top of them.

We're a small, fast-moving founding team with multiple published papers in NeurIPS, ICML, CVPR etc and background from Apple, Amazon, Microsoft, CMU, IIT.

We are backed by world-class investors and leaders like Jeff Dean, Neotribe VC, PearVC, Together Fund and Zapier Fund.

HOW WE WORK

  • Customer obsession — we start with the customer and work backwards
  • Intellectual honesty — ideas matter more than titles; we communicate directly and assume good intent, even in disagreement
  • Bias for action — we build and learn with customers rather than debate in the abstract
  • Extreme ownership — we own outcomes, not just tasks, and see problems through

Why this role exists

Most research roles at this stage hand you a dataset everyone already has and ask you to be marginally better than the last person who tried. Here you get data nobody else has — real clinical reasoning trajectories from practicing physicians — and the room to figure out what to do with it. This is a founding research hire: you'll define the agenda as much as execute it, with direct founder access, real compute, and nothing between an idea and an experiment.

What you'll do

  • Work with real, proprietary clinical data from hospital and clinic partners to surface insights that shape model and product direction
  • Build clinical reasoning models that improve physician and clinic workflows
  • Design and publish benchmarks that expose where current LLMs fall short on real clinical reasoning
  • Evaluate computer-use models on real-world tasks
  • Own the training and evaluation pipeline end to end
  • Take open-ended problems from question to working model, with minimal predefined structure
  • Write up findings as technical reports and papers

Ideal candidate

  • Has real research experience — can define a problem, not just execute a known one
  • Has trained models before (not just fine-tuned APIs) and is fluent in Python
  • Master's or higher in ML or a related field
  • Energized by open-ended problems and ambiguity
  • Wants to publish, not just ship
  • Takes ownership without needing to be guided
  • Genuinely wants a startup over big tech — speed and ambiguity as defaults, not exceptions

Nice to have

  • Prior founder or founding-engineer experience
  • Strong product taste
  • Worked on healthcare datasets before
  • Built LLM-powered products before
  • Ambitions to start your own company someday — we'll support that path

What you get

  • Direct, daily work with the founders, plus exposure to board and investor conversations
  • Real ownership of technical direction, with scope that grows as the company does
  • Full compute and data to do the work properly
  • Competitive salary and meaningful equity
  • Visa sponsorship available

Source: Pear Vc careers (Ashby)

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