IT Systems Manager, AI Administration

Celea Therapeutics
Boston, MA
HybridCareer-pivot friendly

Who this role is best for

Strong fit for IT professionals who administer Microsoft 365 environments and integrate AI tools into workflows, with experience in endpoint management and collaboration technologies in a Boston-based hybrid work arrangement.

Best fit for

  • Candidates with 5+ years in IT administration and AI integration experience in small to medium enterprises
    — “5+ years of experience in IT administration, desktop support, or systems administration.”
  • Individuals who have implemented AI solutions using Microsoft Copilot, ChatGPT, or Claude in enterprise settings
    — “2+ years of experience configuring and implementing AI solutions across small and medium-sized companies.”
  • Professionals skilled in Microsoft 365 and endpoint management with a track record of supporting hybrid work environments
    — “Location: Boston, MA (hybrid)”

Things to consider

  • This role requires managing AI governance and compliance in an enterprise context
    — “Apply AI governance, security, privacy, and responsible-use practices in an enterprise environment.”
  • Candidates must be able to handle both technical and user-facing responsibilities
    — “Serve as a primary point of contact for end-user technical support.”

How to stand out

  • Highlight AI automation projects and Microsoft 365 migration experience in your resume
    — “Support Microsoft 365 migrations, upgrades, and implementation projects.”
  • Demonstrate expertise in Microsoft Intune and Entra ID during interviews
    — “Working knowledge of Microsoft Intune, Entra ID, Exchange Online, and Microsoft Teams.”
  • Showcase your ability to streamline workflows with AI tools like Power Automate
    — “Evaluate, develop, and deploy AI-powered solutions that improve employee productivity.”
Pace · SteadyCollaboration · MediumAutonomy · MediumDecision Impact · Team

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • managing Microsoft 365 services
  • deploying laptops
  • troubleshooting technical issues
  • supporting conference room technology
Typical background
5+ years experience in IT systems managementbackground in Microsoft technologies

Skills & requirements

Required

Microsoft 365 AdministrationEndpoint ManagementUser AdministrationTechnical SupportAI Innovation

Preferred

Call Center ExperienceAdditional Languages

Stack & domain

Microsoft 365Exchange OnlineMicrosoft TeamsSharepoint OnlineOnedrive For BusinessMicrosoft Entra IDIntune Endpoint ManagementWindows LaptopsMobile DevicesEndpoint SecurityAICustomer ServiceTroubleshootingProblem-solvingIT Systems ManagementAI Administration

About the role

Original posting from Celea Therapeutics via Greenhouse

About Celea Therapeutics

Celea Therapeutics is dedicated to advancing transformative treatments for people with serious respiratory diseases. Drawn from the Latin word for “sky,” our name reflects our mission to rise above the status quo and deliver therapies that change lives. Our lead program, deupirfenidone (LYT-100), is currently in Phase 3 clinical development with active candidate enrollment, representing a potential new standard of care for idiopathic pulmonary fibrosis (IPF) and other fibrotic lung diseases.

Rising above the status quo takes a team as strong as its science, and we hire and work by five values: accountability — owning outcomes and acting like owners; transparency — talking straight and building trust; collaboration — achieving together what no one could alone; innovation — challenging accepted ideas and taking smart risks; and passion — bringing energy and heart to the mission. 

We are seeking a skilled and customer-focused IT Systems Manager, AI Administration to support and maintain our Microsoft 365 environment, end-user computing infrastructure, and corporate technology services. This role administers Microsoft 365 services, provisions and deploys laptops, manages user accounts and permissions, troubleshoots technical issues, and supports conference room technology across the organization. 

The ideal candidate is a Microsoft-certified IT professional with strong technical knowledge, excellent customer service skills, and the ability to work effectively in a fast-paced environment. 

Reports to: Vice President, Information Technology | Location: Boston, MA (hybrid) | Employment Type: Full-time 

Key Responsibilities 

Microsoft 365 Administration 

Administer and support Microsoft 365 services: Exchange Online, Microsoft Teams, SharePoint Online, OneDrive for Business, Microsoft Entra ID, and Intune Endpoint Management. 

Manage user accounts, licensing, groups, permissions, and security roles. 

Configure and maintain Microsoft 365 security, compliance, and governance policies. 

Monitor system performance and troubleshoot service-related issues. 

Support Microsoft 365 migrations, upgrades, and implementation projects. 

Endpoint Management & Laptop Deployment 

Build, configure, image, and deploy Windows laptops and mobile devices. 

Manage device lifecycle activities including provisioning, inventory management, refreshes, and decommissioning. 

Configure and maintain endpoint security policies using Microsoft Intune and other management platforms. 

Perform hardware diagnostics, upgrades, and repairs as needed. 

Maintain accurate asset management records. 

User Administration 

Create, modify, and disable user accounts following established processes. 

Manage access requests and permissions based on company security standards. 

Support onboarding and offboarding activities. 

Assist with identity and access management initiatives. 

Ensure compliance with internal security policies and procedures. 

Technical Support & Help Desk 

Serve as a primary point of contact for end-user technical support. 

Diagnose and resolve hardware, software, networking, printing, and mobile device issues. 

Respond to incidents and service requests in accordance with service level agreements. 

Document troubleshooting procedures, solutions, and knowledge base articles. 

Escalate complex issues when required while maintaining ownership through resolution. 

AI Innovation & Automation 

Leverage generative AI platforms, including Microsoft Copilot, ChatGPT, and Claude, to improve productivity, automate workflows, and enhance end-user support. 

Apply AI governance, security, privacy, and responsible-use practices in an enterprise environment. 

Create, configure, implement, and manage AI agents, assistants, and automation solutions for business and IT operations. 

Identify and implement AI-driven solutions that streamline repetitive tasks, improve knowledge management, and increase operational efficiency, while analyzing and maintaining a positive return on investment. 

Use AI tools for troubleshooting, documentation creation, process optimization, data analysis, and user support. 

Leverage Microsoft Copilot Studio, Power Automate, and AI-integrated Microsoft 365 services. 

Evaluate, develop, and deploy AI-powered solutions that improve employee productivity and IT service delivery. 

Partner with business stakeholders to identify opportunities for AI-driven improvements across the organization. 

Promote adoption of Microsoft Copilot and other approved AI technologies through training, support, and best practices. 

Conference Room & Collaboration Technology Support 

Support conference room technologies, including Microsoft Teams Rooms, video conferencing systems, audio/visual equipment, and digital collaboration tools. 

Configure and troubleshoot meeting room hardware and software. 

Ensure conference room systems are operational and available for business meetings. 

Coordinate vendor support and equipment maintenance as necessary. 

Security & Compliance 

Support implementation and enforcement of cybersecurity best practices. 

Monitor and respond to security alerts and incidents. 

Assist with patch management, vulnerability remediation, and endpoint security. 

Ensure compliance with company policies and industry standards. 

Promote security awareness throughout the organization. 

Required Qualifications 

Bachelor's degree in Information Technology, Computer Science, or related field, or equivalent experience. 

5+ years of experience in IT administration, desktop support, or systems administration. 

2+ years of experience configuring and implementing AI solutions across small and medium-sized companies. 

Experience supporting Microsoft 365 environments. 

Experience deploying and managing Windows laptops and mobile devices. 

Working knowledge of Microsoft Intune, Entra ID, Exchange Online, and Microsoft Teams. 

Experience supporting conference room and AV technologies. 

Strong understanding of networking fundamentals and troubleshooting techniques. 

Technical Skills 

Proficiency with operating systems and networks 

Cloud computing skills 

Familiarity with hardware and databases 

Security protocols and cybersecurity best practices 

Basic scripting and coding (PowerShell preferred) 

Microsoft 365 administration 

Microsoft Intune and endpoint management 

Active Directory and Microsoft Entra ID 

Microsoft Teams and Teams Rooms support 

Hardware and software troubleshooting 

Network troubleshooting and connectivity support 

Generative AI platforms (Microsoft Copilot, ChatGPT, Claude) 

AI agent development and workflow automation 

Prompt engineering and AI-assisted productivity tools 

Microsoft Copilot Studio and Power Platform automation 

Soft Skills 

Excellent communication and interpersonal skills 

Self-motivated and strong problem-solving abilities 

Effective time management 

Sound decision-making skills 

Exceptional organizational skills 

Leadership and team collaboration 

Ability to work effectively under pressure 

Customer service orientation 

Strong attention to detail 

Ability to prioritize multiple tasks and projects 

Preferred Qualifications 

Microsoft Certified: Modern Desktop Administrator Associate 

Microsoft 365 Certified: Administrator Expert 

Microsoft Certified: Endpoint Administrator Associate 

CompTIA A+, Network+, or Security+ 

Experience with ITIL-based service management practices 

Experience supporting hybrid cloud environments 

Success Factors 

The successful candidate will be proactive, customer-focused, technically strong, and committed to improving the end-user technology experience while maintaining a secure and reliable IT environment. 

Why Join Celea Therapeutics 

Play a pivotal role in advancing life-changing therapies for patients with devastating lung diseases. 

Shape the foundation of a Phase 3–ready biotech poised for significant growth. 

Collaborate with a passionate, mission-driven leadership team. 

Competitive compensation and equity package. 

Compensation 

Transparency is one of our values, and that includes how we pay. The anticipated salary range for this role is $125,000 to $155,000, plus bonus and equity. Where an offer lands within the range reflects the candidate’s experience, skills, and internal equity — and we welcome open conversations about compensation from the first call, so there are no surprises at the offer stage. 

Actual compensation will be determined based on experience, qualifications, and location.  In addition to base pay, this role is eligible for bonus and equity compensation.

Base Pay Information$125,000—$155,000 USDOur Commitment

Celea Therapeutics is an equal opportunity employer. We evaluate every candidate against the requirements of the role using a structured, evidence-based process, and we make employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other legally protected characteristic.

For more information, visit www.celeatx.com or connect with us on Twitter @celeatx.

Source: Celea Therapeutics careers (Greenhouse)

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