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Posted August 13, 2025. The role appears to have been filled or removed. Check out similar open roles below.

Mechanical Engineer, Fluidics/Perfusion

Until
San Francisco, CA
On-site

Who this role is best for

Geared toward interdisciplinary engineers comfortable with electromechanical design and physical modeling, working in a startup environment in the Bay Area.

Best fit for

  • Candidates with experience in organ perfusion and startup environments will align well with this mission-driven team.
    — “Experience with organ perfusion in a research or clinical context”
  • Individuals with a strong background in heat and mass transfer and fluidic system design are ideal for this role.
    — “Deep understanding of heat and mass transfer principles”

Things to consider

  • The role may demand a high level of independence, given the emphasis on full-stack engineering.
    — “High degree of autonomy across full engineering stack”
  • Candidates must be prepared to work in a fast-paced, scrappy environment as described in the job description.
    — “Desire to join a fast-paced, scrappy engineering team”

How to stand out

  • Highlight experience with fluidic systems and physical modeling in your resume and interview responses.
    — “Experience designing fluidic systems for perfusion/heat exchangers”
  • Emphasize your ability to handle electromechanical design and control software in your application materials.
    — “High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling”
  • Showcase any prior work in cryopreservation or related biological engineering fields.
    — “developing perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware”
Pace · Fast PacedCollaboration · LowAutonomy · HighDecision Impact · Company

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • successful development of perfusion systems
  • vitrification and rewarming hardware
Typical background
graduate level in Mechanical Engineering, Physics

Skills & requirements

Required

Heat And Mass Transfer PrinciplesFluidic Systems DesignElectromechanical DesignControl SoftwarePhysical Modeling

Preferred

Organ Perfusion ExperienceStartup Experience

Stack & domain

Heat And Mass Transfer PrinciplesDesigning Fluidic Systems For Perfusion/heat ExchangersElectromechanical Design And FabricationControl SoftwarePhysical ModelingOrgan Perfusion In A Research Or Clinical ContextExperience Working In A StartupDesire To Join A Fast-paced, Scrappy Engineering TeamMechanical EngineeringPhysics

About the role

Original posting from Until via Lever

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

About You:

  • Track record of exceptional engineering abilities
  • Deep understanding of heat and mass transfer principles
  • Experience designing fluidic systems for perfusion/heat exchangers
  • High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
  • Desire to join a fast-paced, scrappy engineering team

Preferred Qualifications:

  • 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
  • Experience with organ perfusion in a research or clinical context
  • Experience working in a startup

Benefits:

  • Opportunity for outsized impact creating the future as an early team member
  • Generous medical, dental and vision insurance coverage for employees and their dependents
  • Flexible time off and paid holidays
  • Competitive compensation package, including salary and equity
  • Access to a 401(k) retirement savings plan
  • FSA and commuter benefits
  • Subsidized lunch daily

Compensation:

While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.

As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.

Source: Until careers (Lever)

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