ML Research Engineer, Performance Optimization

Lila Sciences
Cambridge +3 more
On-site

Who this role is best for

A natural match if you have experience optimizing large language models on NVIDIA hardware and working in collaborative AI research environments.

Best fit for

  • Candidates with hands-on experience optimizing LLM inference and training at scale on multi-node GPU clusters
    — “Experience running LLM inference and/or training at scale across multi-node GPU clusters.”
  • Individuals who have built and maintained production ML libraries with clean APIs and strong testing
    — “Proven track record of software engineering excellence — clean APIs, well-tested code, thoughtful abstractions.”
  • Professionals with a strong understanding of reinforcement learning and async pipeline optimization
    — “Familiarity with core concepts in reinforcement learning.”

Things to consider

  • The role requires a strong balance between computational optimization and collaboration with researchers
    — “Setting the performance standard: make sure optimized configurations are tested, accessible, and adaptable to research tasks”
  • Candidates must be prepared to work with cutting-edge tools and frameworks like vLLM and Megatron
    — “Experience with LLM inference libraries such as vLLM and training libraries such as Megatron”

How to stand out

  • Highlight experience with both GPU performance tuning and distributed systems in your resume and interviews
    — “GPU compute performance: profiling, kernel development, long-context handling, memory footprint optimization”
  • Demonstrate your ability to create maintainable and reusable ML systems with specific examples
    — “making these optimizations maintainable, reusable, and adaptable”
  • Emphasize your CI/CD expertise with integration testing and automated quality gates for complex systems
    — “Strong CI/CD skills — experience designing integration test suites, build pipelines, and automated quality gates”
Pace · Fast PacedCollaboration · MediumAutonomy · HighDecision Impact · Company

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • maximize GPU utilization
  • optimize GPU cluster performance
  • manage mid-training scale data
  • optimize RL pipeline
  • establish performance standards
Typical background
4+ years of software engineering or machine learning engineering experience

Skills & requirements

Required

LLM Inference LibrariesTraining LibrariesGPU Cluster PerformanceBig Data HandlingRL Pipeline OptimizationSoftware Engineering Excellence

Preferred

Experience With Kernel DslsGPU Networking FrameworksDistributed SystemsContainerized Compute BackendsActor-model Frameworks

Stack & domain

LLM Inference LibrariesTraining LibrariesGPU ClustersReinforcement LearningCI/CDContainerized ComputeSandbox OrchestrationRay ActorsRay ServeLLM Tool UseProblem SolvingTeamworkCommunicationLearningLeadershipMachine LearningPerformance OptimizationGPU ComputingAI Research

About the role

Original posting from Lila Sciences via Greenhouse

Your Impact at LILA

Lila is building a platform where AI and automation co-evolve to accelerate scientific discovery Our AI Research team is looking to hire a ML Research Engineer to maximize iteration speed for mid- and post-training runs on 1T+ parameter LLMs using the latest NVIDIA chips. This involves not only maximizing GPU utilization on an individual training run but also making these optimizations maintainable, reusable, and adaptable so that the rest of the research team always knows how to confidently use the latest optimized stack.

What You'll Be Building

GPU compute performance: profiling, kernel development, long-context handling, memory footprint optimization

GPU cluster performance: collective/MoE framework optimization, comm/compute overlap, RDMA/IB/EFA usage, P/D disaggregation

Big data handling: manage mid-training scale data across storage, streaming, tokenization, and processing

RL pipeline: optimize the async RL cycle, including environment/sandbox interfacing, long rollout handling, large token metadata (such as router replay), and weight sync

Setting the performance standard: make sure optimized configurations are tested, accessible, and adaptable to research tasks so that the whole team can work at maximum velocity

Establishing the Pareto frontier: communicate with researchers about throughput/accuracy tradeoffs (e.g. lower-precision compute, higher async staleness) to establish optimal points

What You'll Need to Succeed

BS/MS in Computer Science or a related quantitative field and 4+ years working as a software engineer or machine learning engineer, or PhD in a relevant research area and 1+ years work experience.

Experience with LLM inference libraries such as vLLM and training libraries such as Megatron, including usage and throughput optimization.

Experience running LLM inference and/or training at scale across multi-node GPU clusters.

Familiarity with core concepts in reinforcement learning.

Proven track record of software engineering excellence — clean APIs, well-tested code, thoughtful abstractions.

Hands-on experience supporting and maintaining production libraries used by other engineers and researchers.

Strong CI/CD skills — experience designing integration test suites, build pipelines, and automated quality gates for multi-package ecosystems.

A passion for agentic systems and awareness of cutting-edge approaches in LLM tool use and autonomy.

Bonus Points For

Experience working with kernel DSLs and frameworks like CUDA, CuTe, CuTile, Triton, etc.

Experience with GPU networking frameworks like NCCL and NIXL, as well as fabrics like NVLink, IB, and EFA.

Experience with distributed systems or compute frameworks (Ray, Flyte, Airflow, or similar).

Familiarity with containerized compute backends (Docker, Modal) and sandbox orchestration.

Experience with Ray actors, Ray Serve, or similar actor-model frameworks.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range$148,000—$240,000 USDAbout LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Source: Lila Sciences careers (Greenhouse)

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