Program Executive, Drug Development and Commercial

Praxis Precision Medicines, Inc.
United States
Remote

Who this role is best for

Aimed at senior-level drug development professionals who thrive in flat, high-ambiguity environments and can lead cross-functional teams.

Best fit for

  • Candidates with cross-functional leadership experience in drug development and a track record of driving program strategy.
    — “Demonstrated drug development experience with a strong track record of cross-functional leadership”
  • Individuals who can operate in a flat organizational structure with high personal accountability and a focus on outcomes.
    — “Comfort operating with limited hierarchy and high personal accountability”

Things to consider

  • The role requires travel despite being a remote position, which may impact work-life balance.
    — “requires the flexibility and willingness to travel as needed”

How to stand out

  • Highlight your ability to lead cross-functional teams and drive strategic decisions in high-ambiguity settings.
    — “lead a cross-functional program team and be responsible and accountable for Praxis’ program strategy”
  • Emphasize your experience in translating strategy into execution under real-world constraints.
    — “Ability to translate strategy into execution, driving decisions that create value under real-world constraints”
  • Showcase your intellectual curiosity and capacity to rapidly understand new therapeutic areas.
    — “Learning agility and intellectual curiosity; ability to rapidly develop deep understanding of new therapeutic areas”
  • Demonstrate your collaborative nature and ability to align teams around a shared vision.
    — “This role is not about coordinating consensus; it is about building alignment”
  • Include examples of how you have taken ownership of program outcomes and made impactful decisions.
    — “retaining clear accountability for program-level decisions”
Pace · Fast PacedCollaboration · HighAutonomy · HighDecision Impact · Company

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • communicate shared vision
  • lead program team
  • drive program execution
Typical background
demonstrated drug development experiencestrong track record of cross-functional leadership

Skills & requirements

Required

Cross-functional LeadershipProgram StrategyIntegrated Development PlanOkrsBudget And Resourcing OversightDecision-makingTeam Effectiveness

Preferred

Drug Development ExperienceFull Development Lifecycle Experience

Stack & domain

Drug DevelopmentCross-functional LeadershipStrategic PlanningBudgetingResource ManagementDecision-makingTechnical OperationsCommercializationResearchCommunicationCollaborationLeadershipProblem-solvingStrategic ThinkingPharmaceuticals

About the role

Original posting from Praxis Precision Medicines, Inc. via Greenhouse

Location:  This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis is looking for a talented and experienced leader for a key program expected to advance best in class or first-in-class products for areas of high unmet medical need. The ideal candidate is a strong, multi-faceted leader who thrives in environments with high ambiguity, limited hierarchy, and real ownership of outcomes as the program continues its rapid trajectory of transformational patient impact.

This results-oriented individual will be characterized by a strong strategic mind, a collaborative nature and intellectual curiosity, and will credibly and enthusiastically work across the spectrum of research, development, technical operations, and commercialization. They will lead a cross-functional program team and be responsible and accountable for Praxis’ program strategy, driving decision-making, and ensuring efficient and high-quality execution.

Praxis is committed to a high-energy, fast-pace and flat organization where individuals work as peers with singular objective to bring drugs to patients. This role is not about coordinating consensus; it is about building alignment, deeply understanding all aspects of the development activities for the product and driving the program forward. The Program Lead must embrace and exemplify this way of working.

Primary Responsibilities

Internally and externally communicate a shared and bold vision for the program.

Lead, manage, and maintain the Program Team, partnering with functional leads to ensure team effectiveness and operational excellence while retaining clear accountability for program-level decisions.

Lead the creation and execution of the program strategy and integrated development plan(s).

In collaboration with the Program Team, define and deliver against program OKRs.

Provide strategic oversight for program budgets and resourcing, actively shaping—not just tracking—investment decisions.

Architect scenarios to inform decision making and program planning; ensure that the right skills and capabilities exist on the team to effectively execute on the program plan.

Be a role model for Praxons: inspire ambitious goals, give and receive direct feedback, and build trust through transparency and follow-through.

“Roll up sleeves and get hands dirty” for the benefit of the team and the program; wear multiple hats, step into gaps, and hold yourself to the same standards as the team.

Serve as the primary integration point with corporate processes without creating unnecessary bureaucracy.

Qualifications and Key Success Factors

Demonstrated drug development experience with a strong track record of cross-functional leadership; experience across the full development lifecycle strongly preferred

Strong holistic understanding of the drug development process across functions

Ability to translate strategy into execution, driving decisions that create value under real-world constraints

Clear, compelling communicator across internal and external stakeholders

What Sets Successful Praxons Apart

Comfort operating with limited hierarchy and high personal accountability

Learning agility and intellectual curiosity; ability to rapidly develop deep understanding of new therapeutic areas

Willingness to challenge assumptions, surface risks early, and engage in healthy debate in service of the best outcome

Demonstrated ability to balance urgency with rigor in fast-moving environments

The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.  You'll need comfort with screen work, basic hand coordination, and focus.  Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Annualized Base Salary$285,000—$325,000 USDCompensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans.  We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! 

Company Overview 

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert

Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Source: Praxis Precision Medicines, Inc. careers (Greenhouse)

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