Scientist II - LC-MS/MS Bioanalysis (Method Development)

KCAS Bio
Kansas City, US
On-site

Who this role is best for

Aimed at mid-level scientists with LC-MS/MS expertise who can work independently in a regulated environment.

Best fit for

  • Candidates with 2–4 years of LC-MS/MS experience in method development and bioanalysis
    — “Bachelor’s or master’s ... with at least 2–4 years of experience with LC-MS/MS”
  • Individuals comfortable with troubleshooting and proposing solutions in a regulated setting
    — “Troubleshoot technical issues and propose solutions with limited guidance”
  • Professionals who value collaboration and can support junior staff in a team-oriented environment
    — “Provide informal guidance to junior staff as needed”

Things to consider

  • Compliance with study protocols and SOPs is a core requirement, not just a preference
    — “Ensure compliance of study activities with pertinent portions of study protocol, SOPs & regulatory requirements”
  • The role requires independent execution of tasks with limited oversight
    — “Independently execute study activities ... with limited oversight”

How to stand out

  • Highlight your experience with small molecule analysis and method optimization in your resume
    — “Experience supporting method development, qualification, and troubleshooting”
  • Emphasize your ability to deliver high-quality results in a regulated environment
    — “Deliver high-quality results with limited oversight”
  • Showcase your data analysis and communication skills for summarizing findings to senior scientists
    — “Analyze data and prepare summaries for senior scientists to aid in client updates”
Pace · SteadyCollaboration · MediumAutonomy · MediumDecision Impact · Team

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • ability to execute study activities independently
  • experience in bioanalytical sample preparation
Typical background
background in chemistry or biochemistryexperience in LC-MS/MS

Skills & requirements

Required

Lc-ms/ms AnalysisMethod DevelopmentData ProcessingTroubleshooting Technical Issues

Preferred

Small Molecule AnalysisProteins, Peptides, Or Biomarkers Experience

Stack & domain

Lc-ms/msBioanalysisMethod DevelopmentQualificationOptimizationData IntegrityTroubleshootingChromatographyProblem SolvingTeamworkCommunication

About the role

Original posting from KCAS Bio via Lever

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist II in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by applying your knowledge of bioanalytical and scientific principles to independently execute study activities, from sample preparation and LC-MS/MS analysis through data processing, while supporting method development, qualification, and optimization. You will utilize your scientific foundation to assess data integrity, troubleshoot technical challenges, and deliver high-quality results with limited oversight.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography–Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to::

  • Execute study activities including sample preparation (extractions, enrichments/affinity capture, digestions), LC-MS/MS analysis, and data processing with limited supervision
  • Support method development, qualification, and optimization activities
  • Troubleshoot technical issues and propose solutions with limited guidance
  • Analyze data and prepare summaries for senior scientists to aid in client updates
  • Ensure compliance of study activities with pertinent portions of study protocol, SOPs & regulatory requirements
  • Communicate study progress and risks to senior staff
  • Provide informal guidance to junior staff as needed
  • Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

To qualify specifically for this role, you will have::

  • Bachelor’s or master’s in chemistry, Biochemistry or chemical/biochemical engineering, or related field with at least 2–4 years of experience with LC-MS/MS
  • Hands-on experience with bioanalytical sample preparation, quantitative LC-MS/MS, and chromatography
  • Experience supporting method development, qualification, and troubleshooting
  • Experience with small molecule analysis; proteins, peptides, or biomarkers experience preferred
  • Familiarity with reversed phase or HILIC chromatography and standard bioanalytical workflows
  • Experience working in a regulated environment (GLP/GxP) preferred

Depending on your background and qualifications, we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.  

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU’LL GET

Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio 

WHO WE ARE

We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to kcasrecruiting@kcasbio.com or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.

IND123

Source: KCAS Bio careers (Lever)

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