Sr Director/Executive Director, Pharm Science Technical Lead

BridgeBio Pharma
San Francisco, CA
On-site

Who this role is best for

Aimed at senior pharmaceutical development leaders who can manage cross-functional teams and navigate complex regulatory environments.

Best fit for

  • Candidates with 15+ years of pharmaceutical or biotech leadership experience and proven regulatory expertise
    — “15+ years of progressive pharmaceutical or biotechnology industry experience”
  • Individuals who have led formulation development and CMC strategy across clinical and commercial-stage programs
    — “responsible for advancing pharmaceutical development and CMC strategy across clinical and commercial-stage programs”
  • Professionals with a track record of managing global CMOs/CDMOs/CROs and executing technology transfer
    — “Experience managing external manufacturing and development partners (CMOs/CDMOs/CROs)”

Things to consider

  • Requires in-office presence 2-3 times per week in San Francisco
    — “This role requires in-office collaboration 2-3x per week in our San Francisco Office”
  • Candidates must be prepared for travel and global regulatory interactions
    — “Represent Pharmaceutical Sciences in interactions with global health authorities”

How to stand out

  • Emphasize experience with lifecycle management and commercial manufacturing in your resume and interview narrative
    — “Experience supporting commercial manufacturing and lifecycle management activities”
  • Showcase leadership in matrixed teams and cross-functional alignment in your professional background
    — “Experience leading multidisciplinary scientific teams in matrixed global organizations”
  • Highlight your ability to influence executive decisions with data-driven recommendations
    — “Influence senior leadership decisions through data-driven scientific and operational recommendations”
Pace · SteadyCollaboration · HighAutonomy · MediumDecision Impact · Company

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • successful pharmaceutical development
  • CMC strategy implementation
Typical background
PhD in pharmaceutical sciences10+ years in biotech/pharmaceutical industry

Skills & requirements

Required

Pharmaceutical DevelopmentRegulatory ComplianceCross-functional LeadershipScientific Expertise

Preferred

AI In BiotechExternal Collaboration

Stack & domain

Pharmaceutical DevelopmentRegulatory And Quality KnowledgeScientific LeadershipFormulation DevelopmentAnalytical DevelopmentProcess DevelopmentManufacturingTechnology TransferRegulatory SubmissionsLifecycle ManagementLeadershipCollaborationAccountabilityPharmaceutical SciencesBiotechClinical And Commercial-stage Programs

About the role

Original posting from BridgeBio Pharma via Greenhouse

Mavericks Wanted 

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on 

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.  

Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work. 

What You’ll Do

The Pharmaceutical Sciences Team Lead (PSTL) is a senior scientific and strategic leadership role responsible for advancing pharmaceutical development and CMC (Chemistry, Manufacturing, and Controls) strategy across clinical and commercial-stage programs. This individual will lead cross-functional pharmaceutical sciences activities spanning formulation development, analytical development, process development, manufacturing, technology transfer, regulatory submissions, and lifecycle management. The role requires a proven leader with deep expertise in pharmaceutical development, strong regulatory and quality knowledge, and the ability to lead high-performing scientific teams in a fast-paced, matrixed environment. The PSTL will serve as a key contributor to corporate development strategy and represent Pharmaceutical Sciences in executive governance, regulatory interactions, and external partnerships.

Responsibilities

Lead high-performing, collaborative, and accountable Pharmaceutical Sciences teams across multiple functional disciplines.

Establish and drive organizational priorities, resource plans, and development goals aligned with corporate objectives.

Identify program risks proactively and implement mitigation strategies to maintain timelines and deliverables.

Provide scientific leadership for formulation development, analytical development, process development, manufacturing, and technology transfer.

Partner with Non-clinical, Clinical, Regulatory, and Commercial organizations to ensure alignment on development priorities and execution.

Represent Pharmaceutical Sciences in governance committees and executive reviews.

Influence senior leadership decisions through data-driven scientific and operational recommendations.

Collaborate with Regulatory Sciences and Regulatory Affairs on CMC strategy, risk mitigation, and agency responses.

Represent Pharmaceutical Sciences in interactions with global health authorities and regulatory inspections, as needed.

Participate in due diligence activities, external scientific collaborations, and business development evaluations.

Build strong relationships with external partners, vendors, and industry organizations.

Implement scalable systems, processes, and metrics to improve development efficiency and execution quality.

Foster an inclusive and performance-oriented culture that embodies company leadership values and behaviors.

Where You’ll Work 

This role requires in-office collaboration 2-3x per week in our San Francisco Office and travel, as needed

Who You Are

PhD or equivalent advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biochemistry, or related scientific discipline preferred.

15+ years of progressive pharmaceutical or biotechnology industry experience, including significant leadership responsibility in Pharmaceutical Sciences, CMC, or Technical Operations.

Experience leading multidisciplinary scientific teams in matrixed global organizations.

Strong knowledge of pharmaceutical development, manufacturing, analytical development, regulatory expectations, and quality systems.

Experience managing external manufacturing and development partners (CMOs/CDMOs/CROs).

Strategic thinker with strong scientific and operational acumen.

Exceptional communication and influencing skills with executive presence.

Proven ability to drive alignment across complex cross-functional organizations.

Strong decision-making and problem-solving capabilities in dynamic development environments.

Prior experience in NDA/MAA submissions and regulatory approvals.

Experience supporting commercial manufacturing and lifecycle management activities.

Familiarity with global supply chain strategy and technical operations.

Experience in both large pharmaceutical and emerging biotech environments preferred.

Travel, as needed

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary$267,000—$331,900 USDAs a global company, our comprehensive benefits may vary based on location.  We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

For BridgeBio Full-Time U.S Based Roles:

Financial & Rewards  

Market-leading compensation   

401(k) with employer match   

Employee Stock Purchase Program (ESPP)  

Pre-tax commuter benefits (transit and parking)  

Referral bonus for hired candidates  

Subsidized lunch and parking on in-office days  

Health & Well-Being  

100% employer-paid medical, dental, and vision premiums for you and your dependents  

Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)  

Fertility & family-forming benefits  

 Expanded mental health support (therapy and coaching resources)  

Hybrid work model with flexibility  

Flexible, “take-what-you-need” paid time off and company-paid holidays  

Comprehensive paid medical and parental leave to care for yourself and your family  

Skill Development & Career Paths: 

People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility 

We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching 

We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities 

Source: BridgeBio Pharma careers (Greenhouse)

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