Senior Director, HR Business Partner – Commercial

Relay Therapeutics
Cambridge, MA
On-siteCareer-pivot friendly

Who this role is best for

Best suited to seasoned HR leaders with biotech/pharma commercial experience working in Cambridge, MA, who can navigate rapid growth and cross-functional collaboration.

Best fit for

  • Candidates with prior experience building commercial teams in biotech or pharma
    — “has built or scaled a commercial organization in biotech or pharma”
  • HR professionals who thrive in dynamic, fast-paced environments and are comfortable with high-volume hiring
    — “execute high-volume, time-sensitive hiring waves”
  • Individuals who can align people strategy with enterprise priorities and launch goals
    — “align the Commercial people strategy with enterprise priorities”

Things to consider

  • This role demands deep integration with field-based teams across multiple states
    — “support a multi-state, field-based workforce”
  • Candidates must be prepared to shape and build new organizational structures
    — “architect and build Relay’s Commercial organization from the ground up”

How to stand out

  • Emphasize your track record in coaching senior leaders during periods of growth
    — “Coach senior commercial leaders — many of whom will be new to Relay”
  • Showcase your ability to design onboarding and integration strategies for field-based roles
    — “Design onboarding and integration experiences for commercial hires and new leaders”
  • Demonstrate your capability to shape scalable HR programs across research and commercial teams
    — “Shape scalable people programs — performance management, talent reviews and succession”
  • Position yourself as a leader who bridges cultures and fosters collaboration
    — “Bridge cultures between long-tenured scientific and development teams and newly hired commercial talent”
Pace · SteadyCollaboration · HighAutonomy · HighDecision Impact · Company

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • Leading people partnership across the Commercial organization
  • Executing high-volume, time-sensitive hiring waves
  • Designing market-competitive compensation structures
  • Building commercial leadership capability
  • Establishing policies and training for a multi-state workforce
Typical background
HR Business PartnerPeople Operations

Skills & requirements

Required

HRBP For Commercial OrganizationsOrganizational StrategyTalent AcquisitionLeadership DevelopmentOnboarding And IntegrationPolicy And Training EstablishmentProcess Improvement

Preferred

Commercial Organization Build

Stack & domain

HRBPCommercial Organization BuildLeadership DevelopmentCommunicationProblem-solvingTeamworkBiotechPharma

About the role

Original posting from Relay Therapeutics via Greenhouse

Relay Tx is a clinical-stage biotech preparing for its transition to a commercial company, and we are looking for a Senior Director, HR Business Partner – Commercial to serve as the senior strategic people partner to our Head of Commercial and Commercial leadership team. This is an opportunity to architect and build Relay’s Commercial organization from the ground up — the structures, talent, and leadership capability needed for a successful first launch — while helping Relay stay true to its culture as it grows. Most importantly, you’ll make an impact by helping to bring life-changing medicines to patients who need them the most!

Reporting to the Chief Administrative Officer as a member of the People leadership team, this role leads people partnership across the Commercial organization, including Sales, Marketing, Market Access, Commercial Operations, and related launch functions.

This role is ideal for a seasoned HR leader who has built or scaled a commercial organization in biotech or pharma, brings deep credibility with commercial executives, and is energized by moving fluidly between enterprise strategy, executive advisory, and hands-on execution during a period of rapid growth.

In this role, you will:

Executive Partnership to Commercial Leadership

Serve as the primary people partner and trusted advisor to the Head of Commercial on organizational strategy, leadership effectiveness, talent, and culture

Translate commercial strategy and launch plans into an integrated people strategy covering organization design, workforce planning, talent acquisition priorities, capability building, and leadership development

Coach senior commercial leaders — many of whom will be new to Relay — on leading through rapid growth, building high-performing teams, and integrating into Relay’s culture and ways of working

Advise on complex and sensitive leadership matters, employee relations, and executive-level decisions with sound judgment, discretion, and a strong understanding of risk

Partner with People leadership to align the Commercial people strategy with enterprise priorities and with partner functions such as Clinical Development and Medical Affairs

Commercial Organization Build & Launch Readiness

Lead the people workstream of Relay’s commercial build, including organization design, phased hiring plans, sequencing of leadership hires, and field force sizing and deployment in partnership with Commercial Operations and Finance

Partner with Talent Acquisition to execute high-volume, time-sensitive hiring waves — senior commercial leaders, field sales and key account teams, and market access roles — with a high bar for quality and fit

Partner with Total Rewards to design market-competitive compensation structures, sales incentive compensation plans, and job architecture for commercial and field-based roles

Design onboarding and integration experiences for commercial hires and new leaders, including field-based and remote employees, that build connection to Relay’s science, mission, and culture

Partner with Legal, Compliance, and People Operations to establish the policies, training, and infrastructure needed to support a multi-state, field-based workforce

Organizational Effectiveness & Talent Strategy

Build commercial leadership capability through talent reviews, succession planning, and development planning for critical roles

Establish clear manager expectations and performance practices suited to a commercial environment, including goal setting tied to launch milestones and field performance

Use people analytics, engagement data, and organizational insights to monitor the health of a fast-growing organization and recommend timely actions

Anticipate capability needs across the commercial lifecycle — from pre-launch through launch and growth — and shape workforce plans accordingly

Enterprise People Strategy & Leadership

Contribute to Relay’s enterprise people strategy and operating model as a member of the People leadership team as the company transitions to commercialization

Shape scalable people programs — performance management, talent reviews and succession, engagement and pulse surveys, and leadership development — that work for research, development, and commercial teams alike

Partner with colleagues on the People, Finance, IT, and Operations teams as part of a seamless business partner model that supports senior stakeholders

Bring an external perspective on commercial HR best practices and help build People team capability as the company scales

Change Management & Culture

Lead change strategies that help the broader organization understand and embrace Relay’s evolution into a commercial company

Bridge cultures between long-tenured scientific and development teams and newly hired commercial talent, fostering collaboration across functions

Serve as a culture ambassador, reinforcing Relay’s values and building an inclusive, high-performing environment as the company grows

Critical Competencies

Business-Focused

Speaks the language of the commercial business — launch planning, field performance, market access — and responds as needs change and the organization scales rapidly

Aligns the people strategy with broader business and launch priorities

Strategic Thinker

Sees the possibilities and thinks “yes, if,” rather than “no, because”

Big-picture thinker who anticipates future trends and consequences and builds people plans ahead of the business

Challenges the status quo and constantly strives for improvement

Gets it Done

Take-charge leader who is resourceful, driven, and motivated to achieve

Comfortable in a fast-paced, dynamic, rapidly growing biotech environment

A “builder” excited by the journey of standing up and nurturing newly formed teams

Demonstrates a sense of urgency to overcome obstacles and achieve measurable results

Connector of People

Communicates clearly, listens, and delivers messages in a “plain language” way

Builds rapport quickly and establishes trust, respect, and confidence with executives and frontline employees alike

Superior written, verbal, and presentation skills

Politically astute, humble, mature, and flexible, with a high level of collaboration and influencing skill

Qualifications & Experience

15+ years of progressive Human Resources experience, including significant senior HR Business Partner experience supporting commercial organizations

Direct experience supporting a biotech or pharmaceutical commercial organization through a product launch; experience building a commercial function from the ground up strongly preferred

Proven track record as a strategic advisor to C-suite and senior commercial leaders, with the ability to influence organizational decisions

Deep expertise in organization design, workforce planning, and large-scale hiring for commercial and field-based teams

Working knowledge of sales incentive compensation, commercial job architecture, and the people practices of field-based, multi-state workforces

Strong expertise in leadership coaching, talent management, performance management, employee relations, and change management

Exceptional executive presence and business acumen, with the ability to connect people strategies to commercial outcomes

Ability to balance enterprise-level strategic thinking with hands-on execution in a fast-paced, evolving environment

Estimated Salary Range: [$193,000 - $275,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#JO1

About Relay Therapeutics

Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.  

Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us! 

Source: Relay Therapeutics careers (Greenhouse)

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