Site Reliability Engineer

Latent
San Francisco, CA
On-site

In the 12 months to 30 Jun 2026, Latent filed 5 H-1B positions classified as Software Developers. Source: U.S. Department of Labor, LCA disclosure data. A record of filings already made, not a commitment to sponsor.

Who this role is best for

Strong fit for infrastructure-focused engineers who design and optimize scalable systems and thrive in a collaborative, in-office environment.

Best fit for

  • Candidates with hands-on experience in Kubernetes, Terraform, and ML deployment pipelines
    — “Deep, demonstrable experience with Kubernetes, Helm, and Terraform.”
  • Individuals who have scaled mission-critical systems in a high-ownership culture
    — “proven ability to architect and maintain complex, distributed systems with high-availability requirements.”

Things to consider

  • Requires in-office presence for five days per week in San Francisco
    — “Excitement about working five days per week in our San Francisco office.”
  • Candidates should be prepared for high-ownership expectations and intense work environment
    — “You have the intensity and technical mastery to own mission-critical infrastructure.”

How to stand out

  • Highlight experience with optimizing deployment pipelines for TypeScript and Python/ML
    — “optimize deployment pipelines for both application code (TypeScript) and machine learning models (Python/ML).”
  • Showcase a track record of owning complex systems and scaling infrastructure
    — “owning complex systems and have a proven track record of scaling mission-critical deployments.”
  • Demonstrate fluency with infrastructure as code tools like Terraform
    — “manage and maintain infrastructure definitions using Terraform.”
Pace · SteadyCollaboration · MediumAutonomy · HighDecision Impact · Team

Derived from job-description analysis by Serendipath's career intelligence engine.

What success looks like

  • design, implement, and maintain production environment
  • optimize deployment pipelines
Typical background
site reliability engineeringdevopsinfrastructure

Skills & requirements

Required

KubernetesTerraformCI/CDPostgreSQLRedisKafka

Preferred

TypeScriptPython/ml

Stack & domain

KubernetesHelmTerraformTypeScriptPythonMLPostgreSQLRedisKafka

About the role

Original posting from Latent via Ashby

ABOUT LATENT

Latent is the enterprise pharmacy intelligence platform. Our clinical AI streamlines prior authorizations, appeals, and 340B compliance, so patients start therapy faster and care teams spend less time on paperwork.

We raised an $80M Series A led by Spark Capital and Transformation Capital, with General Catalyst, McKesson Ventures, Conviction, and Y Combinator. 60+ health systems run on Latent, including Yale New Haven, Mount Sinai, UCSF, and Ochsner. We move fast, operate with high ownership, and build products that directly improve patient care.

THE ROLE

You are the infrastructure expert who enables our rapid product development and guarantees 99.9%+ stability and performance of our clinical AI platform for major health systems. Your focus on operational excellence is directly tied to a patient's access to life-saving treatment.

WHAT YOU'LL DO

As our SRE, you will own the entire production environment and improve the development experience:

  • Infrastructure Ownership: Design, implement, and maintain the production environment, having previously handled 500+ machine deployments.
  • Kubernetes Mastery: Own our containerized infrastructure, leveraging deep expertise in Kubernetes and Helm to manage deployment, scaling, and operational health.
  • CI/CD & Deployment Optimization: Optimize and streamline both the TypeScript and Python/ML deployment pipelines to support high-velocity feature release while maintaining the highest reliability.
  • DevX Support: Support Developer Experience (DevX) work to streamline developer workflows, enhance tool proficiency, and improve CI/CD systems.
  • Infrastructure as Code (IaC): Manage and maintain infrastructure definitions using Terraform.

WHAT WE'RE LOOKING FOR

You have the intensity and technical mastery to own mission-critical infrastructure. You hold yourself and others to high standards and thrive in a high-energy, in-office culture where everyone is in it to win it.

  • Tool Proficiency: You are highly proficient with your tools—you speak command line fluently and have mastered keyboard shortcuts.
  • Ownership: You thrive on owning complex systems and have a proven track record of scaling mission-critical deployments.
  • Automation Drive: You love automating things, always finding new ways to increase your own leverage, and defining standards for operational excellence.
  • Problem Solver: You won't wait for someone else to solve a problem that you're in a position to solve; you are willing to jump into whatever needs to get done.

TECHNICAL QUALIFICATIONS & ENVIRONMENT

  • IaC & Orchestration: Deep, demonstrable experience with Kubernetes, Helm, and Terraform.
  • Scaling Systems: Proven ability to architect and maintain complex, distributed systems with high-availability requirements.
  • Deployment Experience: Hands-on experience optimizing deployment pipelines for both application code (TypeScript) and machine learning models (Python/ML). Also PostgreSQL, Redis, Kakfa.
  • Core Team Member: Excitement about working five days per week in our San Francisco office.

NICE TO HAVE

  • Interest in healthcare, pharmacy, or health technology
  • Uses AI tools in your workflow and is always looking for ways to move faster with them

WHY JOIN LATENT

  • Backed by top-tier investors including General Catalyst, Conviction, and Y Combinator
  • Work alongside a high-caliber team building products our healthcare partners love
  • Work on mission-critical problems at the intersection of AI and healthcare
  • Real ownership and visibility
  • High-impact role on a small, fast-growing team

BENEFITS

  • Competitive compensation, including meaningful equity
  • Medical, dental, and vision insurance for employee and dependents
  • Flexible PTO policy
  • Paid parental leave
  • Fertility and family-building stipend through Carrot

Source: Latent careers (Ashby)

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